A small jar of saffron next to a saffron flower

Saffron is Good for Your Mood

Dave Clarke
This content originally appeared on 

If you’ve ever eaten the Spanish dish paella, you know how beautiful and flavorful saffron can be. Botanical referencesdate back thousands of years.

And modern researchers have identified another potential use for this Middle Eastern herb that contains more than 150 volatile and aroma-yielding compounds.

Life is challenging enough for those suffering from depression. So when medications intended to help have the potential to cause side effects, it makes sense to consider safe, effective alternative treatments. That’s where saffron comes into play.

Saffron as a Natural Antidepressant

A study by Australian researchers published in Human Psychopharmacology: Clinical and Experimental reviewed six studies and concluded that “compared with antidepressant medications,” saffron (Crocus sativus) “had similar antide-pressant efficacy.”


A natural compound can be as effective in reducing symptoms of mild-to-moderate depression as prescription drugs? That’s impressive. Better yet, no side effects.

Saffron Compared to Prescription Antidepressants

Study participants were given 30 milligrams (mg) of saffron divided equally into two daily doses. The control group was treated with commonly prescribed antidepressants, fluoxetine or imipramine. The results, the researchers concluded, were similar in treating patients with mild to moderate depression.

The only difference: Those taking the prescription drugs reported side effects ranging from dry mouth to excess sedation. Those taking the saffron reported no such ail-ments.

Long-term studies of saffron’s antidepressant effects are still needed as none of the studies lasted longer than eight weeks, but the science seems promising.

Effective Dosage

If you’re going to try saffron to mitigate mild to moderate depression, published studies indicate that 15 mg twice a day is effective; up to 5 grams per day is considered safe, but that’s much more than you’ll likely need. Effects, the studies showed, can be felt in as little as a week.


Researchers warned that those who take anti-coagulants or people with blood coagulation disorders should exercise caution in using saffron.